The Uzumaki clan is known for having a very strong and different chakra, shown as kushina's chakra alone can subdue the nine tails for a time. They also have an immense capability in Fuinjutsu(seals). This gave the clan the respect of others even if some of their methods were crude The clan members are also distant relatives to the Senju. All Uzumaki members(excluding naruto) have a blood red colored hair.
-crude sealing methods can lead to self harm
-normaly hunted for their unique chakra
-large, strong, and unique chakra
-insurmountable sealing abilities